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Colorado Springs Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a connection. Inflammation acts as the body’s response system to damaging stimuli (injury, pathogens, metabolic stress – a disc herniation pushing on a nerve!) as it tries to repair itself before the harm was achieved. The Chiropractic TRUhealthDR is always amazed at what the body can do! The Chiropractic TRUhealthDR sees its Colorado Springs chiropractic care as a partner of the body’s system in healing particularly when there is spine pain. Chiropractic care uses many tools like spinal manipulation, exercise, and nutrition to help the body. Melatonin is one nutritional tool that is proving value in its ability to interrupt the inflammatory process related disc herniation that results in back pain, neck pain and other spine related pain.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are related to intervertebral disc degeneration. (1) IL-1 β actually promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body regulates itself down to the cellular level via autophagy, the natural process during which the body’s cells clear out damaged (ie, by inflammation) or unneeded parts. In a new study, melatonin boosted autophagy and reduced the degradation of the disc’s extracellular matrix (technically marked by a decline in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The end conclusion was that melatonin inhibits intervertebral disc degeneration by promoting autophagy. (3) Wow. The Chiropractic TRUhealthDR is inspired by this research to see just how well melatonin can work for Colorado Springs back pain related to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is a very common malady seen at The Chiropractic TRUhealthDR that positive news of melatonin’s benefits are quite exciting. A new study explained how melatonin could modify the extracellular matrix of the disc remodeling process started by IL-1 β. Additionally, melatonin reduced the inflammatory cell collection and reduced the release of connected inflammatory markers IL-1β, IL-6, and TNF-α. With this new finding that melatonin interrupted the IL-1B feedback loop, researchers postulated that melatonin may support the restoration process of intervertebral discs after damage has already been done. (1) The Chiropractic TRUhealthDR continues following the new research regarding the role inflammation plays in Colorado Springs disc degeneration and melatonin’s role in tackling it.

INFLAMMATION AND MELATONIN

The significance of melatonin in assisting to slow or stop painful conditions due to inflammation is rising. The description of melatonin as a multitasking molecule influencing mood, immunity, and energy among other things is quite fitting. It is also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland secretes melatonin naturally. Melatonin impacts the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) processes. (1) Melatonin’s specific effect on inflammation and disc degeneration is most attention-getting to The Chiropractic TRUhealthDR and our Colorado Springs back pain patients.

CONTACT The Chiropractic TRUhealthDR

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she describes how The Cox® Technic System of Spinal Pain Management addresses disc degeneration for relief of chronic low back pain in her patient.

Schedule your Colorado Springs chiropractic appointment with The Chiropractic TRUhealthDR now. We can talk about the role inflammation plays in your back pain experience and how melatonin may address the related disc degeneration.

 
The Chiropractic TRUhealthDR presents new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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"This information and website content is not intended to diagnose, guarantee results, or recommend specific treatment or activity. It is designed to educate and inform only. Please consult your physician for a thorough examination leading to a diagnosis and well-planned treatment strategy. See more details on the DISCLAIMER page. Content is reviewed by Dr. James M. Cox I."